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N-acetyl-L-cysteine and L-cysteine HCl

N-acetyl-L-cysteine (or NAC) and L-cysteine are powerful amino acid antioxidants. Cysteine is an important source of sulfur in human metabolism. N-acetyl-L-cysteine assists in the production of glutathione in the body. Glutathione is one of the most important antioxidants. N-acetyl-L-cysteine is the acetylated form of L-cysteine, which renders it more absorbable. It is used as an antidote for acetaminophen and other chemical poisoning. N-acetyl-L-cysteine is also used in cough syrups due to its mucolytic properties. It naturally lowers the viscosity of the mucus, making it easier to break up.

Cysteine deficiency can lead to decreased production of peptide glutathione, leading further to edema, liver damage, muscle loss, lethargy, skin lesions, and weakness.

L-cysteine can be found in cheese, yogurt, pork, turkey, duck, eggs, wheat germ, and vegetables.

Health benefits of NAC/L-cysteine

  • Powerful antioxidant
  • Important for production of glutathione
  • Supports normal immune system
  • Used as an antidote in poisoning emergencies
  • Has detoxifying properties


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Principal Author: M. Ofiyeva
Date of Initial Publication: 07/05/2007
Last Updated: 09/22/2007