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Manganese is an important trace element required as a nutrient for the activation of enzyme systems involved in protein and energy metabolism. Manganese assists in bone and connective tissue formation, as well as in cholesterol synthesis. Manganese is stored in the liver, kidney, pancreas and bones. Manganese helps the body metabolize thiamine (vitamin B1) and vitamin E.

Manganese deficiency can lead to infertility, weakness, bone deformity, and seizures. Some other more serious, but rare conditions caused by manganese deficiency include hearing problems, atherosclerosis, memory loss and confusion.

Manganese can be found in green leafy vegetables, unrefined cereals, beef liver, lima beans, pinto beans, sweet potatoes, and blackberries.

Health benefits of manganese

  • Needed for normal growth and development
  • Assists in the synthesis and metabolism if lipids
  • Needed for activation of enzyme functions
  • Assists in cholesterol synthesis


RDI/AI—2.3 mg per day
UL—11 mg per day


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Principal Author: M. Ofiyeva
Date of Initial Publication: 07/05/2007
Article Last Updated: 03/10/2011